Proximal/Distal-Active/Repressive CREs

To be more stringent and ensure less overlap, we only consider regions with only active peaks or repressive peaks.

count table

Group ATAC (Overlap) ATAC (Union)
Distal:Active 11,435 12,290
Distal:Repressive 1,613 2,725
Proximal:Active 5,162 5,145
Proximal:Repressive 136 143

Using ATAC (Overlap) as final STARR/MPRA CRE table (Total regions: 18,341)

Group Count
Distal:Active 11,435
Distal:Repressive 1,613
Proximal:Active 5,162
Proximal:Repressive 136

Since we use a more stringent criteria (i.e. remove AR), there were only 5 regions apear to be double counted

Distribution of gc content and region length

We could further view CREs across each assay

Group Count
ASTARR 14,220
WSTARR 16,283
LMPRA 12,764
TMPRA 360

If break each by assay direction

Group Active Repressive
ASTARR 69% 31%
LMPRA 99% 1%
TMPRA 99.7% 0.3%
WSTARR 90% 10%

upset plot (total)

upset plot (active)

upset plot (repressive)