FCC Data

WHG-STARR-seq (WSTARR)

FCC Metadata (WSTARR)

File Name	Group	Sample
WSTARRseq_K562_A001.hg38.Input.rep1.WGS.unstranded.bed.gz	Input	Input.rep1
WSTARRseq_K562_A001.hg38.Input.rep2.WGS.unstranded.bed.gz	Input	Input.rep2
WSTARRseq_K562_A001.hg38.Input.rep3.WGS.unstranded.bed.gz	Input	Input.rep3
WSTARRseq_K562_A001.hg38.Input.rep4.WGS.unstranded.bed.gz	Input	Input.rep4
WSTARRseq_K562_A001.hg38.Output.rep1.WGS.unstranded.bed.gz	Output	Output.rep1
WSTARRseq_K562_A001.hg38.Output.rep2.WGS.unstranded.bed.gz	Output	Output.rep2
WSTARRseq_K562_A001.hg38.Output.rep3.WGS.unstranded.bed.gz	Output	Output.rep3

ATAC-STARR-seq (ASTARR)

Tiling MPRA (TMPRA)

FCC Region Screened (Tiling-MPRA)

Chrom	ChromStart	ChromEnd	Region	Dataset
chr11	4505501	6505900	HBE1	OL45
chr11	32869701	34870100	LMO2	OL45
chr11	61787329	61898348	FADS	OL13
chr16	10001	1173100	HBA2	OL45
chr2	59553301	61553700	BCL11A	OL45
chr20	56391301	58391700	RBM38	OL45
chr8	126735901	128736550	MYC	OL43
chrX	47785501	49880650	GATA1	OL43

Lenti-MPRA (LMPRA)

LMPRA Log2FC (Features)

LMPRA Log2FC (Total)

LMPRA Log2FC (Neg. Ctrl)

LMPRA Log2FC and z score

Figure 1: Distribution of LMPRA Log2 fold change

CRISPRi-HCR FlowFISH (CRISPRi-HCRFF)

ENCODE Link

CRISPRi Growth screen (CRISPRi-Growth)

CRISPR E2G benchmark data (CRISPR-E2G)

EPCrisprBenchmark_ensemble_data_GRCh38.tsv
Biosample: K562
Reference
Ulirsch2016
Gasperini et al., 2019
Wakabayashi2016
Schraivogel et al., 2020
Klann2017
Thakore2015
Xie2017
Fulco2019
Qi2018
Huang2018
Xu2015
Fulco2016

#EP links = 10,412
#Regulated     =   487 (~4.7% of total)
#Not Regulated = 9,924